DeCS Server - List Exact Term

Search on:	KELCH-LIKE ECH-ASSOCIATED PROTEIN 1
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DeCS

Descriptor English:

Kelch-Like ECH-Associated Protein 1

Descriptor Spanish:

Proteína 1 Asociada A ECH Tipo Kelch

Descriptor Portuguese:

Proteína 1 Associada a ECH Semelhante a Kelch

Synonyms English:

KEAP-1 Protein
KEAP1 Protein
KEAP 1 Protein
Kelch Like ECH Associated Protein 1

Tree Number:

Definition English:

An adaptor protein characterized by an N-terminal BTB-POZ DOMAIN and six KELCH REPEATS that functions as a substrate for the E3 UBIQUITIN LIGASE complex. It negatively-regulates NF-E2-RELATED FACTOR 2 by targeting it for ubiquitination and degradation by the PROTEASOME. It also represses genes regulated by ANTIOXIDANT RESPONSE ELEMENTS.

History Note English:

2017

Allowable Qualifiers English:

Record Number:

56536

Unique Identifier:

D000072019

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